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Acamprosate
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Acamprosate is an FDA approved medication which has been shown to help alcoholics stop drinking. Acamprosate can reduce persistent symptoms of abstinence such as insomnia, anxiety, restlessness, and the state of unease and dissatisfaction that comes with not drinking alcohol. Acamprosate is chemically similar to an amino acid and acts on the glutamate neurotransmitter system in the brain. Acamprosate has relatively mild side effects, which are typically limited to stomach upsets or diarrhea. Inconvenience can be the major disadvantage to taking Acamprosate because it must be taken three times a day. Acamprosate doesn’t affect the liver, so it’s often used if someone cannot tolerate naltrexone.